Cygnus® is a family of amnion patch allografts that may be used as a barrier in numerous clinical applications.Cygnus®

The natural properties of amniotic tissue hardness growth factors essential for supporting healing and providing mechanical protection.

About Cygnus®

Amniotic membrane is a semi-transparent and resilient membrane that lines the upper cavity of the placenta. Amniotic tissue acts as an immune-privileged protective barrier during fetal development.

Cygnus is applied as an anatomical barrier that helps provide mechanical protection while supporting healing with endogenous growth factors. The Cygnus proprietary process preserves the natural healing properties of amniotic tissue, maintaining inherent levels of key extracellular matrix molecules, growth factors, and cytokines.

Potential Clinical Applications

  • Spine & Neurosurgery
  • Orthopedics
  • Foot & Ankle
  • Urology
  • Wound & Burn Care
  • OB/GYN
  • Oral Surgery

Growth Factors Released from Cygnus Max after 24 Hours at 37° C

Available in Four Thicknesses

Requires no up-front preparation

Hydrates rapidly in the surgical site

Ambient temperature storage with a 5-year shelf-life

Notch and orientation stickers to designate placement of the epithelial side upwards

E-Beam sterilization provides sterility assurance level (SAL) of 10-6

Safety & Versatility

Amniotic tissue is recovered from healthy mothers who have undergone Cesarean section delivery.

Cygnus is processed in accordance with FDA regulations and AATB standards.

Amniotic tissue has been used for over 100 years with well-documented clinical success.

Cygnus Solo

  • Traditional single layer amnion allograft
  • Derived from the amnion layer of the placental membrane
  • Offered in large sizes to meet physician needs
  • Ideal for numerous surgical and soft tissue applications

Delivering the PROMISE of regenerative healing

Cygnus Matrix

  • Flexible multilayer allograft
  • Derived from the amnion and chorion layers of the placental membrane
  • Approximately 4X thicker than traditional single layer amnion
  • Improved handling and increased workability

Providing mechanical PROTECTION

Cygnus Dual

  • Dual-layer amnion allograft
  • Derived from the amnion layer of the placental membrane
  • Approximately 2X thicker than traditional single layer amnion
  • Available in large sizes for a wide variety of applications

PROPRIETARY dual-layer technology

Cygnus Max

  • Maximum natural thickness allograft
  • Derived from the umbilical cord
  • Approximately 8X thicker than traditional single layer amnion
  • Offers excellent handling characteristics and the ability to be sutured

PRESERVING an array of endogenous growth factors

ThinCygnus® Solo

1x1 cm CAS010100S
2x2 cm CAS020200S
2x3 cm CAS020300S
3x3 cm CAS030300S
4x4 cm CAS040400S
4x6 cm CAS040600S
4x8 cm CAS040800S
7x7 cm CAS070700S
10x10 cm CAS101000S
2x12 cm CAS021200S
10x12 cm CAS101200S

DualCygnus® Dual

4x6 cm CAD040600S
7x15 cm CAD071500S
8x10 cm CAD081000S
9x10 cm CAD091000S
9x11 cm CAD091100S
10x11 cm CAD101100S
10x12 cm CAD101200S

MediumCygnus® Matrix

1x1 cm CAP010100S
2x2 cm CAP020200S
2x3 cm CAP020300S
4x4 cm CAP040400S
4x6 cm CAP040600S
4x8 cm CAP040800S

ThickCygnus® Max

1x2 cm CAM010200S
2x2 cm CAM020200S
2x3 cm CAP020300S
2x4 cm CAM020400S
3x3 cm CAM030300S
3x4 cm CAM030400S
3x6 cm CAM030600S
3x8 cm CAM030800S

Rowlatt, U. (1979). Intrauterine wound healing in a 20-week human fetus. Virchows Arch A Pathol Anat Histol, 381(3), 353–361.

Coolen, N.A. et al. (2010). Comparison between human fetal and adult skin. Archives of Dermatological Research, 302(1), 47–55.

Fairbairn, N.G. et al. (2014). The clinical applications of human amnion in plastic surgery, 67, 662-675.

Niknejad H, Peirovi H, Jorjani M, et al. Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater. 2008;15:88-89.

Delcroix GJ, Namin S, D’Ippolito G, Temple HT, Marshall R. Preserving the natural regenerative potential of amniotic membrane. Vivex Biomedical.


Cygnus®is a Registered Trademark of Vivex Biomedical Inc.

Please refer to Instructions for use for description, handling, storage parameters, indications, contraindications, warnings, precautions, and other important information. A surgeon must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient.

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